My husband suffered from a mild adverse reaction to fluoroquinolone antibiotics three years ago. He went on to develop psoriatic arthritis from his floxing approximately one year later. Psoriatic arthritis is a painful skin and joint inflammatory condition. He avoided taking any medications for this condition until just recently.This past week he saw our rheumatologist who prescribed a brand new drug that has just come out on the market to treat psoriatic arthritis. The drug is called Otezla. The doctor told him that this medication was different than all of the other medications used to treat psoriatic arthritis because it does not suppress the immune system. He told him that the only known side effects that were seen in trials were diarrhea (which is supposed to get better the longer you use it), headaches, indigestion, nausea, vomiting, stomach pain, sinus problems and severe depression. The depression is so severe though and include suicidal ideation.
The doctor suggested that the Otezla, for the most part seemed harmless, and its side effects seemed nothing compared to all the other toxic drugs out there to treat this condition. So, my husband said he would give it a try and started the drug, three days ago.Individuals prescribed this drug begin at a lower dose, 10 mg and titrate up to near a 100mgs within about month. Currently, because Otezla is so new, patients can only get the drug from their doctors. Physicians are being given one month trials of the medications from the pharmaceutical company to offer to their patients. If it works, the patient then orders directly from the manufacturer. Pharmacies are not distributing it yet.