Higher Thyroid Hormone Levels Patients Lose More Weight After Bariatric Weight Loss Surgery

Patients who have higher levels of the thyroid hormone triiodothyronine (T3) lose more weight after bariatricWeight Loss Surgery, new research from Portugal reports. The study results will be presented in a poster Monday, April 3, at ENDO 2017, the annual meeting of the Endocrine Society, in Orlando, Fla.”Bariatric Weight Loss Surgery is the most effective treatment for obesity, and thyroid function plays a central role in body weight regulation. However, the predictors of weight loss after bariatric surgery have remained largely unknown,” said lead author João Sérgio Neves, M.D., Resident of Endocrinology at the São João Hospital and Invited Assistant of the Department of Surgery and Physiology at the Faculty of Medicine of the University of Porto, in Portugal.

“Our study shows that patients with higher T3 levels lose more weight after bariatric Weight Loss Surgery surgery. Our results underscore the future potential for thyroid hormone treatment after bariatric surgery,” Neves said.The research team evaluated 649 patients with morbid obesity and normal thyroid function who underwent bariatric Weight Loss Surgery surgery. Overall, 84.3 percent of patients were women; and on average, patients were 41.8 years of age, with preoperative body mass index (BMI) averaging 44.65 kg/m2.The authors excluded patients with history of thyroid disease, those being treated with levothyroxine or antithyroid drugs and patients with thyroid stimulating hormone (TSH) or free thyroxine (T4) outside the reference range.

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