New Arthritis Pain Treatment
Arthritis Pain Treatment prevent flare-up in the painfully disease are on the horizon after scientists discovered how the body’s defense systems is switched off. Rheumatoid Arthritis is a long-term condition that causes pain, swelling and stiffness in the joints especially the hands, feet and wrists. It is an autoimmune disease when the immune system – which normally fights infection – attacks the cells that line joints by mistake, making them swollen, stiff and painful. Over time, this can damage the joint itself, the cartilage and nearby bone.
But it is unsure what triggers this problem with the immune system. It commonly starts between the ages of 40 and 50 with women three times more likely to be affected than men. (Photo: Getty)Now University of Edinburgh scientists have discovered how compounds produced by the bodies immune system help to reduce inflammation and stop damage to healthy tissues. Therapies based on these compounds could help to treat rheumatoid arthritis and even stop flare ups in the first place. It could also lead to Arthritis Pain Treatment for sepsis, where a body-wide immune reaction causes life-threatening tissue damage.
The compounds – called alpha defensins – are part of the body’s first line of defence against infection by stopping bacteria and other infectious agents from reproducing. Previous research had suggested the compounds may also take action on cells of the immune system to prevent extreme inflammation but until now it was not clear how the process works. Therapies based on these compounds that can help to treat rheumatoid arthritis and even stop flare-up in Experiments with human cells found alpha defenses are released by immune cells called neutrophils when they die.
The overall effect is to limit excessive inflammation, restricting damage to healthy tissues without compromising the body’s ability to clear the infection. Reader and Honorary Consultant in Rheumatology Dr Mohini Gray, of the University’s Medical Research Council Centre for Inflammation Research, said: “This discovery opens the door to new approaches for the Arthritis Pain Treatment and prevention of chronic inflammation.